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Antipsychotics for psychotic disorders are very common now. These are a group of medicines used to treat some severe mental disorders like schizophrenia and mania. These drugs are also known as major tranquilizers. And very useful for their antipsychotic properties.

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Why do we use anti-psychotics?

These drugs are usually recommended to treat the symptoms of episodic schizophrenia. They reduce feelings of anxiety and aggression. The symptoms like depression and hallucinations or delusional thoughts are also treated by antipsychotic medications.

But, before using consult your doctor about it. After a proper physical examination, you will get the right medications for can be taken orally in the form of a pill. Also can be given in the form of injection. These injections are known as depots.

Various kinds of antipsychotics are available near you. Some are slow-release in nature. So, these types of drugs require you to have one injection every 2 to 4 weeks interval.

Antipsychotics for schizophrenia

Drugs like antipsychotics are very much useful for psychotic patients. These can give a better solution for schizophrenia, caused by bipolar disorders. They can do it by blocking the chemical effect( dopamine) on the brain. And it reduces acute schizophrenic episodes.

A psychotic disorder like schizophrenia needs early detection and treatment. The detection should be done within five years after the first acute episode. As it’s a peak period for abnormal changes in the brain.

After detection, interventions are playing a vital role. In interventions, rehabilitation programs without medications are meaningless. So, to give an effective treatment the physician adds antipsychotic agents. The drug doses are fully based on the patient’s response.

How do antipsychotics work?

Antipsychotics are the chemicals blocking agents. They simply block the chemicals like dopamine, serotonin, noradrenaline, and acetylcholine in the brain.

Indirectly, these chemicals are responsible for your changing behaviors, mood, and emotions. dopamine is one of them on which the antipsychotics that have an effect.

By blocking the effects of chemicals in the brain the drugs are preventing some psychotic symptoms like delusions, hallucinations, thought disorders, and schizophrenia, mania like bipolar disorders.

What are the types of antipsychotics?

There are mainly two types of antipsychotics :

  • Typical antipsychotics
  • Atypical antipsychotics

What are typical antipsychotics?

The typical antipsychotics also called first-generation antipsychotics, developed in the 1950s. These are the older group of medications known as conventional antipsychotics.

It works by blocking the dopamine-2 receptors. It can be further divided into two types.

  • High potency antipsychotics
  • Low potency antipsychotics

In high potency antipsychotics, they have a higher affinity for the receptors like dopamine and less affinity for the receptors like muscarinic and alpha-adrenergic. 

Low potency antipsychotics are the opposite of high potency drugs. They are very rarely used. Because they are having less affinity for dopamine and a high affinity for the receptors like histamine, muscarinic, and alpha-adrenergic.

Typical antipsychotic medications are like;

  • Chlorpromazine(Thorazine)
  • Fluphenazine(Prolixin)
  • Haloperidol(Haldol)
  • Perphenazine(Trilafon)
  • Thioridazine(Mellaril)
  • Thiothixene(Navane)
  • Trifluoperazine(Stelazine)

What are atypical antipsychotics?

Atypical antipsychotics are also known as second-generation or newer-generation antipsychotics. They were developed in the 1990s.

The medications are like;

Note: Clozapine is the only FDA-approved medication for treating schizophrenia that is resistant to other treatments. ( sources;

When are antipsychotics usually prescribed?

These drugs are mainly prescribed by the psychiatrist. They are usually helped to treat dementia in older people. Also, treat schizophrenia and mania caused by bipolar disorders as well as depression and anxiety.

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